最新研究发现，孕妇患上乳癌后，所面对的死亡和癌症复发危险，并不比其他年轻乳癌病人来得大。
早先的小型调查认为，怀孕会使乳癌患者的病情恶化，但是这次最大规模调查的结论与之相反。
美国得克萨斯大学安德森癌症中心的彼得尔说：“只要发现早，就能取得兼顾大人和孩子的治疗结果。”
一般来说，怀孕妇女尤其害怕患上乳癌，因为既要治疗母亲又要避免伤害到胎儿。有些医生则建议孕妇流产，以便集中精力治疗母亲。
彼得尔研究小组在《癌症》杂志发表最新调研报告，该小组分析了1973年至2006年期间在安德森癌症中心治疗乳腺癌的652名患者的资料。
这些病人年龄都在35岁或者以下，包括了104个怀了身孕的妇女。其中51人怀孕期间确诊为乳癌，另外53人在一年后患上这种病。研究人员调查了她们患癌后连续10年的随访资料，发现在癌症复发、扩散和存活率方面，上述病人跟其他乳癌患者基本相同。调查还发现，孕妇的乳癌通常发现时已属晚期，这可能是因为病人和医生都忽略了乳房的变化。
乳癌对年轻女性侵害较大，她们的存活率也明显要低。医学人员认为年龄可能是病变因素，但目前还不清楚怀孕是不是原因之一。彼得尔说，在最新调查中，没有发现怀孕妇女肿瘤生长比较快的证据。（生物谷Bioon.com）
生物谷推荐原始出处：
Cancer，DOI：10.1002/cncr.24165，Beth M. Beadle，George H. Perkins
The impact of pregnancy on breast cancer outcomes in women 35 years
Beth M. Beadle, MD, PhD 1, Wendy A. Woodward, MD, PhD 1, Lavinia P. Middleton, MD 2, Welela Tereffe, MD 1, Eric A. Strom, MD 1, Jennifer K. Litton, MD 3, Funda Meric-Bernstam, MD 4, Richard L. Theriault, DO 3, Thomas A. Buchholz, MD 1, George H. Perkins, MD 1 *
1Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
2Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
3Department of Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
4Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
BACKGROUND:
Some evidence suggests that women with pregnancy-associated breast cancers (PABC) have a worse outcome compared with historical controls. However, young age is a worse prognostic factor independently, and women with PABC tend to be young. The purpose of the current study was to compare locoregional recurrence (LRR), distant metastases (DM), and overall survival (OS) in young patients with PABC and non-PABC.
METHODS:
Data for 668 breast cancers in 652 patients aged 35 years were retrospectively reviewed. One hundred four breast cancers (15.6%) were pregnancy-associated; 51 cancers developed during pregnancy and 53 within 1 year after pregnancy.
RESULTS:
The median follow-up for all living patients was 114 months. Patients who developed PABC had more advanced T classification, N classification, and stage group (all P < .04) compared with patients with non-PABC. Patients with PABC had no statistically significant differences in 10-year rates of LRR (23.4% vs 19.2%; P = .47), DM (45.1% vs 38.9%; P = .40), or OS (64.6% vs 64.8%; P = .60) compared with patients with non-PABC. For those patients who developed breast cancer during pregnancy, any treatment intervention during pregnancy provided a trend toward improved OS compared with delaying evaluation and treatment until after delivery (78.7% vs 44.7%; P = .068).
CONCLUSIONS:
Young patients with PABC had no statistically significant differences in LRR, DM, or OS compared with those with non-PABC; however, pregnancy contributed to a delay in breast cancer diagnosis, evaluation, and treatment. Primary care and reproductive physicians should be aggressive in the workup of breast symptoms in the pregnant population to expedite diagnosis and allow multidisciplinary treatment. Cancer 2009. ? 2009 American Cancer Society.
