国一项最新研究显示，常喝咖啡可降低患头颈癌的风险。
头颈癌包括口腔癌、鼻癌、鼻窦癌、唾液腺癌及淋巴癌等。美国犹他州大学的研究人员在最新一期《癌症流行病学、生物标志与预防》杂志上报告说，他们对国际头颈癌流行病学联合会提供的9项研究数据进行分析后发现，常喝咖啡的人患口腔癌和咽喉癌的几率要比不常喝咖啡的人低39％。如果每天喝4杯以上的咖啡，这一效果会更加明显。
研究人员解释说，咖啡中所含的抗氧化物等多种化学物质可能是其有抗癌效果的原因之一，但要了解其具体的抗癌机制还需更深入的研究。此前美国和英国的研究曾显示，常喝咖啡可降低前列腺癌、神经胶质瘤和脑瘤等患病风险。（生物谷Bioon.net）
生物谷推荐最新肿瘤会议：第一届上海肿瘤基础和转化医学前沿研讨会，2010
http://www.canceraisa.com/
生物谷推荐原文出处：
CEBP doi: 10.1158/1055-9965.EPI-10-0191
Coffee and Tea Intake and Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
Carlotta Galeone1,2, Alessandra Tavani1, Claudio Pelucchi1, Federica Turati1,2, Deborah M. Winn3, Fabio Levi4, Guo-Pei Yu5, Hal Morgenstern8, Karl Kelsey9, Luigino Dal Maso10, Mark P. Purdue3, Michael McClean11, Renato Talamini10, Richard B. Hayes6, Silvia Franceschi12, Stimson Schantz5, Zuo-Feng Zhang14, Gilles Ferro12, Shu-Chun Chuang15, Paolo Boffetta7,13, Carlo La Vecchia1,2 and Mia Hashibe12,16
Background: Only a few studies have explored the relation between coffee and tea intake and head and neck cancers, with inconsistent results.
Methods: We pooled individual-level data from nine case-control studies of head and neck cancers, including 5,139 cases and 9,028 controls. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI), adjusting for potential confounders.
Results: Caffeinated coffee intake was inversely related with the risk of cancer of the oral cavity and pharynx: the ORs were 0.96 (95% CI, 0.94–0.98) for an increment of 1 cup per day and 0.61 (95% CI, 0.47–0.80) in drinkers of >4 cups per day versus nondrinkers. This latter estimate was consistent for different anatomic sites (OR, 0.46; 95% CI, 0.30–0.71 for oral cavity; OR, 0.58; 95% CI, 0.41–0.82 for oropharynx/hypopharynx; and OR, 0.61; 95% CI, 0.37–1.01 for oral cavity/pharynx not otherwise specified) and across strata of selected covariates. No association of caffeinated coffee drinking was found with laryngeal cancer (OR, 0.96; 95% CI, 0.64–1.45 in drinkers of >4 cups per day versus nondrinkers). Data on decaffeinated coffee were too sparse for detailed analysis, but indicated no increased risk. Tea intake was not associated with head and neck cancer risk (OR, 0.99; 95% CI, 0.89–1.11 for drinkers versus nondrinkers).
Conclusions: This pooled analysis of case-control studies supports the hypothesis of an inverse association between caffeinated coffee drinking and risk of cancer of the oral cavity and pharynx.
