最新一期《美国流行病学期刊》(American Journal of Epidemiology)报道，经常久坐的生活型态，可能会提高罹患大肠癌的风险。
之前曾有医学研究报告指出，如果工作方式属于经常久坐，得大肠直肠癌的风险可能因此提高。但是，这些过去调查的研究对象，多半都是在某段特定时间当中针对某种职业的工作者进行调查。
最新一期的《美国流行病学期刊》则刊登澳洲科学家的最新医学研究指出，如果在日常生活中常常久坐，也可能会提高罹患大肠癌的风险。
在这项研究当中，科学家以918名大肠癌患者在2005年至2007年之间的就业数据、生活型态以及体能活动进行分析，并以1021名民众做为对照组。
统计结果显示，如果超过10年以上都是从事久坐类型的工作，得大肠癌的风险比从来不曾从事静态工作者高2倍，得到结肠癌的风险也比不曾从事静态工作者增加44%。（生物谷Bioon.com）
生物谷推荐原文出处：
American Journal of Epidemiology DOI：10.1093/aje/kwq513
Long-Term Sedentary Work and the Risk of Subsite-specific Colorectal Cancer
Terry Boyle*, Lin Fritschi, Jane Heyworth and Fiona Bull
Research suggests that sedentary behavior may increase the risk of some chronic diseases. The aims of the study were to examine whether sedentary work is associated with colorectal cancer and to determine whether the association differs by subsite. A total of 918 cases and 1,021 controls participated in a population-based case-control study of colorectal cancer in Western Australia in 2005–2007. Data were collected on lifestyle, physical activity, and lifetime job history. The estimated effects of sedentary work on the risk of cancers of the proximal colon, distal colon, and rectum were analyzed by using multinomial logistic regression. Compared with participants who did not spend any time in sedentary work, participants who spent 10 or more years in sedentary work had almost twice the risk of distal colon cancer (adjusted odds ratio = 1.94, 95% confidence interval: 1.28, 2.93) and a 44% increased risk of rectal cancer (adjusted odds ratio = 1.44, 95% confidence interval: 0.96, 2.18). This association was independent of recreational physical activity and was seen even among the most recreationally active participants. Sedentary work was not associated with the risk of proximal colon cancer. These results suggest that long-term sedentary work may increase the risk of distal colon cancer and rectal cancer.
