12月6日,国际著名杂志British Journal of Cancer在线发表了英国研究人员的一项研究成果“The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010。”该研究报告显示,逾四成的癌症患者因为生活习惯欠佳而患癌,这些习惯包括抽烟、喝酒及饮食不当等。
英国每年诊断出的13万癌症患者中,有近半数都因生活习惯太差,其中香烟是最大杀手,23%的男性及15.6%的女性都因为香烟而患癌。第二大杀手则是男性较少摄取新鲜蔬果及女性体重过重。
负责进行这项研究的巴金教授指出,许多人认为患癌是因为自己运气不好,或是体内有癌症基因,从研究调查结果来看,四成以上的癌症病例事实上都是可以避免的。
巴金教授提出防癌建议:男性最重要的是戒烟,摄取更多的蔬果,同时减少饮用酒精饮料。女性要防癌最重要的也是戒烟,但同时要注意体重 。研究显示,1/10的乳癌患者是因为过重。
报告同时显示,食道癌患者半数是因为摄取的蔬果太少,另有1/5的患者是因为饮酒。如口腔癌及喉癌等癌症,则几乎都是因为生活习惯太差而引起的。(生物谷Bioon.com)
doi:10.1038/bjc.2011.474
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The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010
D M Parkin
The overall objective of the study is to estimate the percentage of cancers (excluding non-melanoma skin cancer) in the UK in 2010 that were the result of exposure to 14 major lifestyle, dietary and environmental risk factors: tobacco, alcohol, four elements of diet (consumption of meat, fruit and vegetables, fibre and salt), overweight, lack of physical exercise, occupation, infections, radiation (ionising and solar), use of hormones and reproductive history (breast feeding). The number of new cases attributable to suboptimal exposure levels in the past, relative to a theoretical optimum exposure distribution, is evaluated. For most of the exposures, the attributable fraction was calculated based on the distribution of exposure prevalence (around 2000), the difference from the theoretical optimum (by age group and sex) and the relative risk per unit difference. For tobacco smoking, the method developed by Peto et al (1992) was used, which relies on the ratio between observed incidence of lung cancer in smokers and that in non-smokers, to calibrate the risk. This article outlines the structure of the supplement – a section for each of the 14 exposures, followed by a Summary chapter, which considers the relative contributions of each factor to the total number of cancers diagnosed in the UK in 2010 that were, in theory, avoidable.