根据发表于《英国癌症杂志》(BJC)上的一项研究,摄入过多加工过的肉食品可能增加胰腺癌风险。
这项研究由瑞士癌症基金会和斯德哥尔摩卡罗林斯卡医学院资助。研究发现,与那些不吃肉的人相比,每天摄入50克、100克、150克加工过的肉食品(相当于一根香肠或2片培根)的人患胰腺癌的风险分别增加19%、38%、57%。
每天摄入100克加工过的肉食品比每天摄入50克加工过的肉食品的人患胰腺癌的风险增加19%。
红肉增加男性而非女性患胰腺癌风险的证据尚无定论。结果显示,与不吃肉的人相比,每天摄入120克加工过的肉食品的男性患胰腺癌的风险增加29%。
摄食加工过的肉食品使患胰腺癌的风险增加19%,这看似可能很高--但它是在患胰腺癌几率相对来说很小的基础上的一个增加。在英国,在整个一生中男性和女性患胰腺癌的几率分别为1/77和1/79。
相对而言,吸烟使患胰腺癌风险增加74%。
研究人员分析了涉及超过6000名胰腺癌患者的11项研究数据。
卡罗林斯卡医学院副教授Susanna Larsson说:"胰腺癌患者存活率较差。所以早期诊断很重要,了解什么因素能增加胰腺癌风险也同样重要。"
"如果饮食不影响患胰腺癌风险,那么这可能会有益于公众的健康意识,从源头上帮助减少患胰腺癌疾病的患者数目。"
2008年,在英国大约有8090人被诊断患胰腺癌,占到了所有癌症病例的3%--大约7780人死于胰腺癌。
英国癌症研究中心信息主任Sara Hiom说:"肉类是否是一个确定的胰腺癌风险因子尚未最终定论,需要开展更大规模的研究来证实这一点。但这项新的分析表明,加工的肉类在胰腺癌疾病中可能扮演了一个角色。"
"我们知道,在各种生活方式因素中,吸烟显著增加了患胰腺癌的风险。戒烟是降低自身患各种癌症及其他疾病最好的方式。"(生物谷bioon.com)
doi:10.1038/bjc.2011.585
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Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies
S C Larsson and A Wolk
Abstract: background: Whether red and processed meat consumption is a risk factor for pancreatic cancer remains unclear. We conducted a meta-analysis to summarise the evidence from prospective studies of red and processed meat consumption and pancreatic cancer risk. methods: Relevant studies were identified by searching PubMed and EMBASE databases through November 2011. Study-specific results were pooled using a random-effects model. results: Eleven prospective studies, with 6643 pancreatic cancer cases, were included in the meta-analysis. An increase in red meat consumption of 120 g per day was associated with an overall relative risk (RR) of 1.13 (95% confidence interval (CI)=0.93–1.39; Pheterogeneity<0.001). Red meat consumption was positively associated with pancreatic cancer risk in men (RR=1.29; 95% CI=1.08–1.53; Pheterogeneity=0.28; five studies), but not in women (RR=0.93; 95% CI=0.74–1.16;Pheterogeneity=0.21; six studies). The RR of pancreatic cancer for a 50 g per day increase in processed meat consumption was 1.19 (95% CI=1.04–1.36; Pheterogeneity=0.46). conclusion: Findings from this meta-analysis indicate that processed meat consumption is positively associated with pancreatic cancer risk. Red meat consumption was associated with an increased risk of pancreatic cancer in men. Further prospective studies are needed to confirm these findings.