近日,刊登在新一期《英国癌症杂志》上瑞典的一项新研究"Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies"显示,经常吃西方食谱中经过加工的肉类与胰腺癌患病风险升高之间存在关联。
瑞典卡罗琳医学院在上报告说,与不吃加工肉的人相比,如果某人每天食用50克加工肉,例如一根香肠或两片培根,那么其患胰腺癌的几率要高出19%。与不食用红肉(包括牛肉、羊肉、猪肉)的男性相比,每天吃120克红肉的男性患胰腺癌的几率会高出29%,但此次研究未发现红肉对女性胰腺有何显著影响。
这项研究由卡罗琳医学院和瑞典癌症基金会共同发起,研究人员对涉及6000名胰腺癌患者的11项研究结果进行分析对比。负责该研究的卡罗琳医学院副教授苏珊娜·拉尔松说,胰腺癌患者的存活率很低,为帮助患者尽早得以诊治,了解该病的诱发原因很重要。
该报告还援引英国癌症研究中心信息主管萨拉·霍姆的话说,尽管现在还无法百分之百地确定加工肉是否是罹患胰腺癌的决定性因素,更多的研究结果正等待进一步分析,但这些新数据可以提醒人们注意可能存在的诱因。(生物谷Bioon.com)
doi:10.1038/bjc.2011.585
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Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies
S C Larsson1 and A Wolk1
Background:
Whether red and processed meat consumption is a risk factor for pancreatic cancer remains unclear. We conducted a meta-analysis to summarise the evidence from prospective studies of red and processed meat consumption and pancreatic cancer risk.
Methods:
Relevant studies were identified by searching PubMed and EMBASE databases through November 2011. Study-specific results were pooled using a random-effects model.
Results:
Eleven prospective studies, with 6643 pancreatic cancer cases, were included in the meta-analysis. An increase in red meat consumption of 120?g per day was associated with an overall relative risk (RR) of 1.13 (95% confidence interval (CI)=0.93–1.39; Pheterogeneity<0.001). Red meat consumption was positively associated with pancreatic cancer risk in men (RR=1.29; 95% CI=1.08–1.53; Pheterogeneity=0.28; five studies), but not in women (RR=0.93; 95% CI=0.74–1.16; Pheterogeneity=0.21; six studies). The RR of pancreatic cancer for a 50?g per day increase in processed meat consumption was 1.19 (95% CI=1.04–1.36; Pheterogeneity=0.46).
Conclusion:
Findings from this meta-analysis indicate that processed meat consumption is positively associated with pancreatic cancer risk. Red meat consumption was associated with an increased risk of pancreatic cancer in men. Further prospective studies are needed to confirm these findings.