8月22日，“针灸横切声波作用新发现”新闻发布会在香港举行。由香港大学、北京大学等学校组成的研究团队经过八年研究发现，利用磁共振摄影技术，实际观察到针灸震动所产生的横切声波启动了细胞内钙离子流及钙震荡，从而达到减轻患者痛苦和治疗的作用。这一研究成果刊登在最新一期《欧洲生理学学报》期刊上。(生物谷 Bioon.com)
doi:10.1038/nchem.1114
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Signaling and Cell PhysiologyPhysiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave
Geng Li, Jie-Ming Liang, Pei-Wen Li, Xiaoqiang Yao, Peter Zhong Pei, Wei Li, Qi-Hua He, Xifei Yang, Queenie C. C. Chan and Paul Y. S. Cheung, et al
This article presents a novel model of acupuncture physiology based on cellular calcium activation by an acoustic shear wave(ASW) generated by the mechanical movement of the needle. An acupuncture needle was driven by a piezoelectric transducer at100 Hz or below, and the ASW in human calf was imaged by magnetic resonance elastography. At the cell level, the ASW activatedintracellular Ca2+ transients and oscillations in fibroblasts and endothelial, ventricular myocytes and neuronal PC-12 cells along with frequencyamplitudetuning and memory capabilities. Monitoring in vivo mammalian experiments with ASW, enhancement of endorphin in blood plasmaand blocking by Gd3+ were observed; and increased Ca2+ fluorescence in mouse hind leg muscle was imaged by two-photon microscopy. In contrast with traditional acupuncture models,the signal source is derived from the total acoustic energy. ASW signaling makes use of the anisotropy of elasticity of tissuesas its waveguides for transmission and that cell activation is not based on the nervous system.
