生物谷报道:目前有关人类胚胎干细胞的研究越来越受到关注,但是国内朋友可能对其概况可能还不是很熟悉,生物谷经过精心整理,将全球相关研究概况奉献给大家,请大家继续关注生物谷有关精彩报道。注:转载本文请注明来源于生物谷,并提供链接。
目前已在NIH注册的人类胚胎干细胞总共有26株,6个单位开发的。另外,还有20多株尚未在NIH注册,如韩国,瑞典,英国的成功建系的人类ES细胞。
1、 Allan Robins, Ph.D.
Senior Vice President and Chief Scientific Officer
BresaGen, Inc.
NIH Code: BG01, BG02, BG03, BG04*
Provider's Code: hESBGN-01, hESBGN-02, hESBGN-03, hESBGN-04*
NIH Code BG01 BG02 BG03 BG04*
Provider's Code (hESBGN.01) (hESBGN.02) (hESBGN.03) (hESBGN.04)*
Embryo
Source IVF Clinic IVF Clinic IVF Clinic IVF Clinic
Category Fresh Fresh Fresh Fresh
IVF Status Discarded—unacceptable for further use Discarded—unacceptable for further use Discarded—unacceptable for further use Discarded—unacceptable for further use
Characteristics
Passage # > 70 > 40 > 35 < 5
Mouse Feeder Cells
Used in Isolation Yes Yes Yes Yes
Karyotype Normal Normal 46XX TBD
Stem Cell Immuno Markers: + +
SSEA-1 - - - -
SSEA-3 + + + +
SSEA-4 + + + +
TRA 1-60 + + + TBD
TRA 1-81 + + + TBD
Oct-4 + + + TBD
Alkaline
Phosphatase + + + +
Gender Male Male Female TBD
Frozen/Thawed:
Short-term Yes Yes Yes Yes
Long-term Yes Yes Yes TBD
Pluripotent Yes Yes Yes TBD
Commercialization
Available 43 16 25 No
(The cells failed to expand into undifferentiated cell cultures.)
Price $5,000 + actual shipping cost $5,000 + actual shipping cost $5,000 + actual shipping cost NA
# Shipped 30 12 3 NA
Total 45
TBD = To be Determined; NA = Not Applicable