生物谷报道：人类以前对食肉菌的认识很少，本周Science上报道的这篇研究揭示了食肉菌是如何进入猎物体内，然后杀死猎物，最终分解各种水解酶将肉类分解的过程的机理。
A Predator Unmasked: Life Cycle of Bdellovibrio bacteriovorus from a Genomic Perspective
Snjezana Rendulic,1 Pratik Jagtap,1* Andrea Rosinus,1* Mark Eppinger,1* Claudia Baar,1* Christa Lanz,1 Heike Keller,1 Carey Lambert,2 Katy J. Evans,2 Alexander Goesmann,3 Folker Meyer,3 R. Elizabeth Sockett,2 Stephan C. Schuster1
Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.
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